Going back to release, there has been one specific thing about AI defensive rotations and assignments that has been killing the game for me and driving me nuts.
When bringing the ball up the court, nobody picks up the trail man.
If the trail man is a capable shooter, I get plenty of wide open 3s each game. Going small or playing a stretch 4 has never been so effective. Heck, he doesn't even have to be a 3 point shooter...an athletic guy can use the space to drive straight to the hoop. At least that's how I scored half of my points the little bit of time I played MyCareer.
I was playing a game with Dirk at the 4, and late in the game I realized my usage patterns for Dirk are completely different than in real life because of it. Check this:
I took my time and waited to shoot for effect. This is Dirk Freakin' Nowitzki, and the defense couldn't care less. The problems extend beyond allowing open 3s, too:
Are you kidding me? They just let him walk right up the hoop. This obviously isn't an every play occurrence, but it happens far too frequently.
Like I said, this has been bugging me ever since release...the patches really haven't seemed to do anything. I think I'm really noticing it even more now that I'm playing games where either Dirk or PG13 are playing the 4 and scoring mad buckets. I really hope this is something that can be fixed, or requires a small adjustment on my part. I find myself running an actual half court offense far too infrequently and it's tanking my enjoyment of the game.
Also, would like to give another +1 to checking out the MyLeague/MyGM "Fix-It List" over on OS. There are some really important tuning suggestions in that thread that I imagine could be accomplished this year and would have a tremendous impact on the mode.